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Chapter 38
Circulation
11
Biology
Undergraduate 1
04/16/2009

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Term

 Circulatory system? Purpose? Fluid must be able to?

Definition
The purpose is to maintain a proper volume, composition, and temperature of interstitial fluid. The fluid that surrounds cell must be capable of supporting cell live. CV system must deliver O2 and nutrients to the cell and remove CO2 and other waste products. 
Term
Components of CV systems?
Definition

1) Pump, Heart:

-fish: two chambered

-Amphibians: three chambered 

-Birds and mammals: four chambered with 

2) Vessels: arteries, veins, and capillaries

3)Blood: fluid of system

Term
Open and closed systems?
Definition

-Some organisms have open circulatory systems such as mollusk and anthropoids. In this situation blood leaves the vasculature and mixes with interstitial fluid, then re-enters through openings in pumps or vessels. 

-Close system is found in most animals. Blood stays in vessels but fluid and molecules can leave and return due to pressure. 

Term
Blood? Functions? Amount? Consist of?
Definition
Blood transports, CO2,O2, nutrients, solutes, wastes, hormones, immune cells. Helps regulate temperature and pH. There is 4 to 6 liters of blood in humans. Plasma portion 50% to 60% of total volume. Cellular portion 40% to 50% of total volume. 
Term
Blood disorders?
Definition

-Anemia: deformed because of insufficient amount of RBC's of hb resulting in reduced ability to carry O2.

-Chronic: reduce production or blood loss. 

-Hemmorrhagic: sudden blood loss.

-hemolytic: lysis of RBC from protists or bacteria.

-B12 defiency: often vegetarians get.

-sickle cell or thalessemias (globin affected)

-polycythemias: too many red blood cells

-leukemias: increased White Blood Cell production (cancer). 

 

Term
Blood types? Rh factor?
Definition

-Type A has antibodies to type B markers. Type AB has neither A nor B markers. Type B has antibodies to type A markers. Type O has antibodies for A and B markers. 

-Rh+ have the Rh marker. Rh- will make antibodies after Rh+ if exposed. Erythroblastosis fetalis: 2nd Rh+ child. 

Term
Vessels? Such as arteries and veins?
Definition

Arteries: Intimia(endothelium), media (smooth muscle), adventitia (mostly CT) 

-carry Oxygenated blood mostly

-high pressure, little resistance, smooth out pulse of heart (systolic vs. diastolic pressure)

- Adventitia contains symp nerves to regulate flow

Veins: less smooth muscle and elastin fibers

-lower pressure, return deox blood, have valves.

Term
Movement of blood components? At arterial end of capillary? At venous end of capillary?
Definition

At arterial end of capillary: ultrafiltration 

-35mm hydrostatic pressure vs 25mm net osmotic pressure leads to net exit of fluid. 

At venous end of capillary: reabsorption 

-15mm hydrostatic pressure vs 25mm net osmotic leads to net influx of fluid. 

* rest of interstitial fluid returns to veins via lymphatic system. 

* muscle pump aids return to heart. 

Term
What about capillaries? 
Definition

- Most a single layer of epithelium (endothelium) with a basement membrane. 

- Continuous Capillaries: endothelial cells joined by tight junctions and clefts (can pull apart and increase permeability). 

-Fenestrated Capillaries: have small holes or fenestration's that allow more rapid movements of small particles. 

Term
Blood pressure?
Definition

-Arterial pressures in large vessels are what are usually measured. 

-Systolic vs. diastolic 

- Pressure changes as one moves from arteries to 

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