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Chapter 16 Blood
Chapter 16 Blood
24
Physiology
03/21/2011

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Term
What does plasma consist of?
Definition
water, ions, organic molecules, gases.
Term
What are the 3 plasma proteins?
Definition
albumins
globulins
fibrinogens
Term
What are the 3 cellular components of blood?
Definition
RBCs
WBCs
Platelets
Term
What is another name for RBCs?
Definition
erythrocytes
Term
What is another name for WBCs?
Definition
Leukocytes
Term
What is another name for platelets?
Definition
Thrombocytes
Term
What is one thing that platelets and RBCs have in common?
Definition
neither have a nucleus
Term
What are the 5 types of WBCs?
Definition
Lymphocytes
Monocytes
Neutrophils
Eosinophils
Basophils
Term
Why does liver degeneration lead to edema?
Definition
because liver produces plasma proteins and if there are a lack of these, the water will remain outside of blood and cause edema
Term
Does blood consist more of plasma or RBCs?
Definition
Plasma 58%
RBCs 42%
Term
What is Hematocrit?
Definition
ratio of RBCs to plasma
Term
Why and How are new RBCs formed?
Definition
the kidney senses a decrease in the amount of O2 carrying.
Kidney sends erythropoietin to bone marrow which then makes more RBCs (erythropoiesis)
Term
What organ makes Erythropoetin and which makes Thrombopoetin?
Definition
Kidney makes Erythropoetin Liver makes Thrombopoeitin
Term
Lifespan of RBCs?
Definition
120 days
Term
Anemia
Definition
not enough hemoglobin, so blood cant carry O2 well enough
Term
3 main stages of hemostasis
Definition
1) vasoconstriction
2) temporary blockage by platelet plug
3) blood coagulation/clot formation
Term
What can aspirin do for clotting?
Definition
aspirin is an antithromboxane which disallows for clotting
Term
What can TPA do for clotting?
Definition
activates plasmin which gets rid of existent clots
Term
Intrinsic Pathway in Coagulation
Definition
caused by collagen exposure. activates Factor 12
Term
Extrinsic Pathway in coagulation
Definition
damaged tissues expose tissue factor 3. This activates factor 7.
Term
What is the role of Thrombin in coagulation?
Definition
Thrombin converts fibrinogen to fibrin which causes clotting.
Term
What is the role of Plasmin?
Definition
Plasmin is made from plasminogen by thrombin and TPA. Plasmin breaks down fibrin polymers into fibrin fragments to get rid of clot at the end.
Term
What is the purpose of Folic Acid in blood?
Definition
Folic acid is a B12 vitamin that creates Thymine which helps make RBCs. Decrease in Folic Acid leads to decreased RBCs and ultimately anemia.
Term
Polycythemia
Definition
when your hematocrit is too high, just like in dehydration, except this time it is because you overproduce RBCs