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Chapter 13
Viruses
45
Microbiology
10/25/2012

Additional Microbiology Flashcards

 


 

Cards

Term

In which of the following ways do viruses differ from bacteria?

A viruses are filterable

B viruses are obligate intracellulare parasites

C viruses don't have any nucleic acid

D viruses are not composed of cells

E viruses don't reproduce

 

Definition
D viruses are not composed of cells
Term

Which of the following staements providesthe most significant support for the idea that viruses are nonliving chemicals?

A they are not composed of cells

B they are filterable 

C they cannot reproduce themselves outside a host

D they cause diseases similar to those caused by chemicals

E. they are chemically simple

Definition
C they cannot reproduce themselves outside a host
Term

Which of the following statements about spikes is false?

A they are for penetration

B they are used for absorption

C they may cause hemaggllutination

D they are found only on enveloped viruses

E they are found only on nonenveloped viruses

Definition
A they are for penetration
Term

Which of the following is not used as a criterion to classify viruses?

A biochemical tests

B morphology

C nucleic acid

D size

E number of capsomeres

Definition
A biochemical tests
Term

Which of the following is not a method of culturing a virus?

A in lab animals

B in culture media

C in embryonated eggs

D in cell culture

E none of the above 

 

Definition

B in culture media

 

Term

Bacteriophages and animal viruses do not differ significantly in which one of the following steps?

A adsorption

B penetration'

C uncoating

D biosynthesis

E release

Definition
D biosynthesis
Term

The definition of lysogeny is

A phage DNA is incorporated into host cell DNA

B lysis of the host cell due to a phage

C the period during replication when virions are not present

D when the burst time takes an unusully long time

E attachment of a phage to a cell

Definition
phage DNA is incorporated into host cell DNA
Term

A viroid is

 

A a complete, infectious virus particle

B a nonenveloped, infectious piece of RNA

C a capsid without a nucleic acid

D a provirus

E an infectious protein

Definition
B a nonenveloped, infectious piece of RNA
Term

In figure 13.1 which structure is a compex virus

 

A a

B b

C c

D d

E all of the above

Definition

B b

Note: it the one with legs

Term

In figure 13.1 the structure illustrated are composed of 

A DNA

B RNA

C DNA or RNA

D capsomeres

E Capsids

Definition
D capsomeres
Term

 A clear area against a confluent "lawn" of bacteria is called a 

A phage

B pock

C cell lysis

D plaque

E rash

Definition
D plaque
Term

Continuous cell lines differ from primary cell llines in that

A viruses can be grown in continuous cell lines

B continuous cell lines always have to be reisolated from animal tissues.

C continuous cell lines are derived from primary cell lines

D continuous cell lines can be maintained through an indefinite number of generations.

E. Continuous cell lines are from human embryos.

Definition
D continuous cell lines can be maintained through an indefinite number of generations.
Term

Which of the following is necessary fro replication of a prion?

A DNA

B DNA polymerase

C lysozymes

D pSc

E RNA

Definition
D pSc
Term

A persistent infection is an infection in which

 

A the virus remains in equilibrium with the host without causing a disease

B viral replication is unusually slow

C the disease process occurs gradually over a long period

D host cells are graduallylysed

E host cells are transformed

Definition

C the disease process occurs gradually over a long period

 
Term

Which of the following statements is false

A a prophage is phage DNA inserted into a bacterial chromosome.

B a prophage can pop out of the chromosome

C prophage genes are represented by a repressor protein coded for by the prophage.

D a prophage may result in new properties of the host cell

E the prophage makes the host cell immune to infection by other phages

Definition
E the prophage makes the host cell immune to infection by other phages
Term

Lysogeny can result in all of the following except

A innumity to reinfection by the same phage

B acquisition of new characteristics by the host cell

C immunity to reinfection by any phage

D transduction of specific genes.

E none of the above. 

Definition
C immunity to reinfection by any phage
Term

Which of the following would be the first step in biosynthesis of a virus with a - strand of RNA

 

A synthesis of DNA from an RNA template

B synthesis of double stranded RNA from an RNA template

C synthesis of double stranded RNA from a DNA template

D transcription of mRNA from DNA

E synthesis of DNA from a DNA template

Definition

B synthesis of double stranded RNA from an RNA template

 

Term

An infectious protein is a 

A bacteriophage

B prion

C retrovirus

D viroid

E papovavirus

Definition
B prion
Term

An envelope is acquired during which of the following steps?

A pentration

B adsorption

C uncoating

D Biosynthesis

E release

Definition
E release
Term

Which of the following contributes to the difficulty in establishing etiology of cancer?

A most viral particles can infect cells without inducing cancer

B cancer may not develop until long after infection

C cancers do not seem to be contagious

D viruses are difficult to observe

E all of the above

Definition
E all of the above
Term

An example of a latent viral infection is

 

A subacute sclerosing panencephalitis

B cold sores

C influenza

D smallpox

E mumps

 

Definition
B cold sores
Term

The most common route of accidental AIDS transmission to health care workers is 

A mouth to mouth

B fecal oral

C needlestick

D aerosol

E environmental surface contact

 

Definition
C needlestick
Term

Assume you have isolated an unknown virus.  It is a single stranded RNA enveloped virus.  To which group does it most likely belong?

A herpesvirus

B picornavirus

C retrovirus

D togavirus

E papovavirus

Definition
D togavirus
Term

To which group does a small, nonenveloped single stranded RNA virus most likely belong?

A herpesvirus

B picornavirus

C retrovirus

D togavirus

E papovavirus

Definition
B picornavirus
Term

The most conclusive evidence that viruses cause cancers is provided by 

A finding oncogens in viruses

B the presence of antibodies against viruses in cancer patients

C cancer following injection of cell-free filtrates

D treating cancer with antibodies

E some liver cancer patients having hepatitis

 

Definition
C cancer following injection of cell-free filtrates
Term

Bacteriophages derive all of the following from the host cell except

A lysozymes

B tRNA

C amino acids

D nucleotides

E ATP

Definition
A lysozymes
Term

Generalized transduction differs from specialized transduction in that generalized transduction

A kills the host

B transfers DNA from one cell to another

C transfers specific DNA

D involves lysogeny

E lyses the host cell

Definition
C transfers specific DNA
Term

Generally in a DNA containing virus infection, the host animal cell supplies all of the following except

A RNA polymerase

B nucleotides

C DNA polymerase

D tRNA

E all of the above are supplied by the host animal cell 

Definition
C DNA polymerase
Term

Pput the following in correct order for DNA virus replication:

1 maturation, 2 DNA synthesis, 3 transcription, 4 translation

A 1,2,3,4

B 2,3,4,1

C 3,4,1,2,

D 4,1,2,3

E 4, 3,2,1

Definition
B 2,3,4,1
Term

A viral species is a group of viruses that

 

A have the same morphology and nucleic acid

B have the same genetic information

C infect the same cells and cause the same disease

D can't be defined

Definition
B have the same genetic information
Term

Viruses that have reverse transcriptase are in the 

A retroviridae and picornaviridae

B herpesviridae and retroviridae

C hepadnaviridae and retroviridae

D Bacteriophage families

E influenzavirus

 

Definition
C hepadnaviridae and retroviridae
Term

DNa made from an RNA template will be incorporated into the virus capsid of 

A retroviridae

B herpesviridae

C hepadnaviridae

D bacteriophage families

E influenzavirus

Definition
C hepadnaviridae
Term

Which of the following statements about viruses is false?

 

A viruses contain DNA or TNA but never both

B viruses contain a protein coat

C virues use the anabolic machinery of the cell

D viruses use their own catabolic enzymes

E viruses have genes

 

Definition
D viruses use their own catabolic enzymes
Term

Approximately how many virus particles could fit along a 1-millimeter line?

A 2

B 20

C 200

D 20,000

E 2,000,000

Definition
D 20,000
Term

Some viruses, such as human herpesviruses 1, infect a cell without causing symptoms; these are called

 

A latent viruses

B lytic viruses

C phages

D slow viruses

E unconventional viruses

Definition
A latent viruses
Term

Assume a patient had chickenpox (human herpesvirus 3) as a child.  Which line on the graph in figure 13.2 would show the number of viruses present in this person as a 60 year old with shingles (human herpesvirus 3)

A a 

B b

C c

D d

E e

Definition
E e
Term

Assume a patient has influenza.  During which time (on the graph in figure 13.2) would the patient show the symptoms of the illness.

 

A a

B b

C c

D d

E e 

Definition
C c
Term

The following steps occur during multiplication of herpes viruses.  What is the the third step?

 

A attachment

B biosynthesis

C penetration

D release

E uncoating

Definition
E uncoating
Term

The following steps occur during multiplication of retroviruses.  What is the the fourth step?

 

A synthesis of +RNA

B attachment

C penetration

D release

E uncoating

Definition
A synthesis of +RNA
Term

Nontoxic strains of Vibrio cholerae can become toxic when they are in the human intestine with toxic strains of bacteria.  This suggests that the toxin genes are acquired by

A host enzymes

B prions

C reverse transcriptase

D transduction

E none of the above

Definition
D transduction
Term

Which of the following steps does not occur during multiplication of a picornavirus?

A synthesis of + strands of RNA

B synthesis of -strands of RNA

C synthesis of viral protiens

D synthesis of DNA.

E none of the above

Definition
D synthesis of DNA.
Term

Which of the following is most likely a product of an early gene?

A capsid proteins

B DNA polymerase

C envelope proteins

D spike proteins

E lysozyme

 

Definition
B DNA polymerase
Term

Most RNA viruses carry which of the following enzymes?

 

A DNA-dependent DNA polymerase

B lysozyme

C RNA dependent RNA polymerase

D reverse transcriptase

E ATP synthase

 

Definition
C RNA dependent RNA polymerase
Term

The following steps occur during biosynthesis of a +strand RNA virus.  What is the third step?

A attachment

B penetration and uncoating

C synthesis of -strand RNA

D synthesis of +strand RNA

E synthesis of viral proteins

 

Definition
C synthesis of -strand RNA
Term

What contributes to antigenic shift in influenza viruses?

A worldwide distribution

B segmented genome

C attachment spikes

D ease of transmission

E different subtypes

Definition
B segmented genome