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Cardio Test 2
ACS Brand Generics
13
Pharmacology
Graduate
03/17/2013

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Cards

Term
Clopidogrel
Definition
Plavix
P2Y12
300mg PO (Loading)- skip if fibrinolysis > 75
75mg PO Daily
600mg PO if PCI
Hold CABG for 5 days
Term
Prasugrel
Definition
Effient
P2Y12
60mg Loading, 10mg Maint
5 mg if < 60kg
avoid in > 75 years
Hold CABG 7 Days
Term
Ticagrelor
Definition
Brilenta
180mg loading, 90mg BID
Dyspnea and Ventricular Pauses
Hold CABG for 3-5 days.
Term
Abciximab
Definition
Reopro
12 Hours
Term
Tirofiban
Definition
Aggrastat
18-24 hours
Decrease Infusion Rate 50% CrCl < 30
Term
Eptifibatide
Definition
Integrillin
18-24 hours
Decrease infusion rate 50% CrCl < 50
Term
Heparin
Definition
UFH
60 u/kg IV Bolus
12 u/kg/hr IV Maint
Term
Enoxaparin
Definition
Lovenox
1 mg/kg SQ Q12H (look up NSTEMI IV BOLUS)
.5 mg/kg IV for STEMI PCI
CrCl < 30 Q24H
CrCl < 15 AVOID
Term
Fondaparinux
Definition
Atrixia
MM: 2.5mg SQ daily
Fibrinolysis: 2.5mg IV then 2.5mg SQ daily
CrCl < 50: CAUTION
CrCl < 30: AVOID
Term
Bivalirudin
Definition
Angiomax
CrCl < 30 decrease dose
Dialysis: Even Lower
PCI ONLY, gp2a3b unnessecary
Term
Alteplase
Definition
Activase
1 Bolus + Continous Infusion
Term
Reteplase
Definition
Retavase
2 Bolus
Term
Tenecteplase
Definition
TNKase
1 Bolus
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