Shared Flashcard Set

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Cardio 9 (vasculitis)
Cardio First Aid 2012
20
Medical
Professional
06/07/2013

Additional Medical Flashcards

 


 

Cards

Term
What is Raynaud's disease?
Definition
Decreased blood flow to fingers or toes in response to cold temp or emotional stress (turn white)
Term
What is Raynaud's phenomenon?
Definition
Raynaud's disease secondary to a mixed connective tissue disease, SLE, or CREST syndrome
Term

Temporal (giant cell) arteritis:

- Who

- Cause

- 4 Symptoms

Definition

Who: elderly

Cause: focal granulomatous inflammation in branches of the carotid artery

Symptoms: unilateral headache, jaw claudication, irriversible blindness, polymyalgia rheumatica

Term

Takayasu's arteritis:

- Who

- Cause

- 6 Symptoms

Definition

Who: Young asian females

Cause: granulomatous thickening of aortic arch proximal to great vessels

Symptoms: weak upper extremity pulses (pulseless), fever, night sweats, arthritis and myalgias, skin nodules, ocular problems

Term

Polyarteritis nodosa:

- Who

- Cause

- 3 Symptoms

Definition

Who: young adults

Cause: immune complex mediated transmural fibrinoid necrosis of renal and visceral vessels (NOT lung)

Symptoms: depends on where it is, but hypertension, neuro dysfunction, cutaneous eruptions

Term

Kawasaki disease:

- Who

- 6 Symptoms

Definition

Who: Asian kids <4

 

Symptoms:

Fever

lymphadenitis

conjunctivitis

strawberry tongue

hand-foot erythema

desquamation

Term

Buerger's disease (thromboangiitis obliterans):

- Who

- Cause

- 2 Symptoms

Definition

Who: young men who are heavy smokers

Cause: segmental thrombosing vasculitis

Symptoms: Raynaud's phenomenon, intermittent claudication leads to gangrene of digits

Term

Microscopic polyangiitis:

- Cause

- 2 Symptoms

- 2 Lab findings

Definition

Cause: immune

Symptoms: glomerulonephritis, palpable purpura

Labs: no granulomas, p-ANCA

Term

Wegener granulomatosis:

- Cause

- Symptoms

- 2 lab findings

Definition

Cause: necrotizing vasculitis and necrotizing granulomas

Symptoms: upper respiratory, lower respiratory, and renal involvement

Labs: c-ANCA, large nodular densities on CXR

Term

Churg-Strauss syndrome:

- Who

- Cause

- 4 Symptoms

- 2 lab findings

Definition

Who: Asthma patients

Cause: immune- granulomatous vasculitis with eosinophilia

Symptoms: sinusitis, palpable purpura, peripheral neuropathy (wrist or foot drop), can involve other organs too

Labs: p-ANCA, eosinophilia

Term

Henoch-Schönlein:

- Who

- Cause

- 3 Symptoms

Definition

Who: children

Cause: IgA immune complexes

Symptoms: palpable purpura on buttocks/legs, arthralgia, abdominal pain with melena

Term

Sturge-Weber disease:

- Cause

- 4 Symptoms

Definition

Cause: congenital vasculitis of capillaries

Symptoms: port-wine stain on face, ipsilateral leptomeningeal angiomatosis (intracerebral arteriovenous malformation), seizures, early onset glaucoma

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Term
What are the upper respiratory symptoms in Wegener granulomatosis? (4)
Definition

Perforation of nasal septum

chronic sinusitis

otitis media

mastoiditis

Term
What are the lower respiratory symptoms in Wegener granulomatosis? (2)
Definition

Necrotizing granulomas:

hemoptysis

dyspnea

Term
What are the renal symptoms in Wegener granulomatosis? (2)
Definition

Necrotizing glomerulonephritis:

hematuria

red cell casts

Term
How do you treat Wegener granulomatosis? (2)
Definition

cyclophosphamide

corticosteroids

Term
What is the most common childhood systemic vasculitis?
Definition
Henoch-Schönlein
Term
Which vasculitis is associated with Hep B?
Definition
Polyarteritis nodosa
Term
How do you treat Kawasaki disease?
Definition
IV immunoglobulin and aspirin
Term
What complication can occur in Kawasaki disease?
Definition
coronary aneurysm
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