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BYU Tissue
Exam 1
45
Histology
09/14/2010

Additional Histology Flashcards

 


 

Cards

Term
Plasma Membrane
Definition
Selective
Amphipathic
Fluid
Possibly the brain of the cell
Term
Nucleus
Definition
Euchromatin-Loose DNA
Heterochromatin-Dense DNA
Term
sER

rER
Definition
Makes new membrane,hormones, stores ions

makes proteins to be secreted
Term
Ribosomes
Definition
-All proteins start on a free ribosome
-Ribosomes do not have a membrane
-They are made in the nucleolus
Term
Endosomes
Definition
Include: lysosomes, peroxisomes(free radical defense), vacuoles
Term
Cytoskeleton
Definition
3 Main varieties: microtubule, intermediate filament, microfilament
Term
Microtubule
Definition
largest, hollow tube, polymer, originates in MTOC, stabalized by MAPs, has motor proteins
Term
Intermediate Filament(IF)
Definition
IF- purely structural, doesn't move
Over 50 types
Cell specific
Term
Microfilaments
Definition
smallest
actin arrayed in parallel fashion,
for motility
pinocytosis/phagocytosis
anchoring
Term
Capacitation
Definition
Takes 5 hours
Triggered by bicarbonate in vagina
Increases sperm metabolism/motility
Term
Barriers to Egg
Definition
Corona Radiata- "sticky cells", granulosa cells in hyaluronic acid

Zona Pellucida- composed of glycoproteins

Egg plasma membrane
Term
Capacitated Sperm heads have:
Definition
Hyaluronidase activity
Term
Acrosomal Rxn
Definition
Sperm rxn that happens at egg. Glycoproteins match up with egg.
-Release of enzymes to break through corona radiata
Term
Cortical granules
Definition
Cortical granules release their contents outside the egg.
Term
Embryo Stages
Definition
4 cell stage- embryonic genome turned on

16 cell stage-Morula
Term
Compaction
Definition
Outer cells flatten, tight junctions form-->placenta
Inner cells form gap junctions-->fetus
Term
Week 1 of Fertilization
Definition
Fertilization, cleavage, compaction, implantation(day 7)
Term
Blastocyst Formation
Definition
-Depends on compaction
-Allows fluid between inner cells
-Results: Inner Cell Mass, Blastocoel, trophoblast
Term
Week 2 After Fertilization
Definition
Trophoblast Splits-forms chorion(placenta)
-Cytotrophoblast-inner layer
-Syncytiotrophoblast- outer layer, buries into
uterus
Inner Cell Mass splits
-epiblast-amnion-->exercise/cushion for fetus
-hypoblast-yolk sac-->blood/gut formation, umbilicus
Term
Week 3 After Fertilization
Definition
Gastrulation and somites
Term
How do cells know to move?
Definition
Due to chemoattraction and chemorepulsion
Term
Basement Membrane
Definition
Filters between epithelial and CT
Controls cell growth, metabolism and differentiation
Term
2 Derived components of Basement Membrane
Definition
Epithelial-basal lamina
CT-lamina fibroretiularis
Possible 3rd layer- lamina lucida
Term
Function of Epithelial
Definition
Protects, Absorbs, Secretes, Transports, Contracts, Filters, Sensory

Pretty abs seek turkey cubes for sandwiches.
Term
Microvilli
Definition
Increase absorption 30 fold
May be part or product of cell
Enclosed in cytoplasm
Term
Cilia
Definition
Made of 10 doublets of microtubules w/ 1 in the center
Arise from centriole and basal body
Dynein and ATP used to cause motion
Contained within membrane.
Term
Glycocalyx
Definition
Sugar coating used for recognition, adhesion, absorption, and protection
Term
General Epithelial attachments
Definition
Lateral-Cadherin based
Basal-Integrin Based
Zonula-Band
Macula- A spot
Term
Tight Junctions
Definition
&-Most apical
-Tetraspanins make sealing strands- occludin claudins
Term
Adherens Junctions include
Definition
Zonula Adherens, Desmosomes, Hemidesmosomes
3 parts-transmembrane proteins, anchoring proteins, and cytoskeleton.
Term
Zonula Adherens
Definition
Needed for all other junctions to form
Transmembrane cadherins bind to actin
Term
Macula Adherens
Definition
Also called desmosomes
Anchoring proteins attach to Intermediate filaments.
Term
Gap Junctions
Definition
Channel called Conexon
Made by 6 connexins.
Term
Epithelial Cell Turnover
Definition
Can happen in 4-5 days(gut) or 28 days(skin)
Keratinocytes immediately fill in the gap.
Term
Epithelial Mesenchyme Transitions(EMTs)
Definition
Cells diminish E-cadherin expression, protrude out of epithelium and break down cell junctions.
-Then the cell becomes mesenchymal and differentiates.
An example is gastrulation
Term
How to tell the difference between secretory cells:
Definition
It's all about the organelle content and expansion.
Term
Protein Secreting Cells
Definition
-Well developed rER.
-Highly Polar: basal rEr and apical secretory granules
Term
Mucin Secreting Cells
Definition
Well developed basal rEr and supranuclear Golgi
Lots of mucin filled vesicles
Term
Mucin facts
Definition
-Hydrophillic
-GAGs are repeating disaccharides(up to 40)
-100s of GAGs per mucin
-Becomes mucus when full of water
-85% Carb
Term
Lipid(steroid) secreting Cells
Definition
-Well developed sEr
-Free lipid vavuoles
-Lots of mitochondria w/tubular cristae
Term
Ion and water transport secretion
Definition
-Folded membrane
-Lots of mitochondria at folds
-tight junctions between cells
Term
Mucous Secretions

Serous Secretions
Definition
Mucous: viscous, slimy, glycosylated. ie goblet cells

Serous: watery, poorly or non glycosylated. ie sweat glands
Term
Stains
Definition
-Hemotoxylin & Eosin(H&E)- Most common, nuclei/ribos/rER blue, cytoplasm/proteins pink
-Diff-Quick-Stains blood cells
-Orcein-Resourcein- elastic fibers black, nuclei gray
-Silver Stain-Neurons black
-Supravital-Stains reticulocytes, chromatin dark
Term
What is an organ?
Definition
Two or more different tissues that have a certain function and shape
Term
Hatching
Definition
Aided by enzyme in trophoblast
Also aided by uterine secretions