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Selective Amphipathic Fluid Possibly the brain of the cell |
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Euchromatin-Loose DNA Heterochromatin-Dense DNA |
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Makes new membrane,hormones, stores ions
makes proteins to be secreted |
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-All proteins start on a free ribosome -Ribosomes do not have a membrane -They are made in the nucleolus |
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| Include: lysosomes, peroxisomes(free radical defense), vacuoles |
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| 3 Main varieties: microtubule, intermediate filament, microfilament |
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| largest, hollow tube, polymer, originates in MTOC, stabalized by MAPs, has motor proteins |
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| Intermediate Filament(IF) |
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IF- purely structural, doesn't move Over 50 types Cell specific |
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smallest actin arrayed in parallel fashion, for motility pinocytosis/phagocytosis anchoring |
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Takes 5 hours Triggered by bicarbonate in vagina Increases sperm metabolism/motility |
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Corona Radiata- "sticky cells", granulosa cells in hyaluronic acid
Zona Pellucida- composed of glycoproteins
Egg plasma membrane |
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| Capacitated Sperm heads have: |
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Sperm rxn that happens at egg. Glycoproteins match up with egg. -Release of enzymes to break through corona radiata |
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| Cortical granules release their contents outside the egg. |
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4 cell stage- embryonic genome turned on
16 cell stage-Morula |
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Outer cells flatten, tight junctions form-->placenta Inner cells form gap junctions-->fetus |
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| Fertilization, cleavage, compaction, implantation(day 7) |
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-Depends on compaction -Allows fluid between inner cells -Results: Inner Cell Mass, Blastocoel, trophoblast |
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| Week 2 After Fertilization |
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Trophoblast Splits-forms chorion(placenta) -Cytotrophoblast-inner layer -Syncytiotrophoblast- outer layer, buries into uterus Inner Cell Mass splits -epiblast-amnion-->exercise/cushion for fetus -hypoblast-yolk sac-->blood/gut formation, umbilicus |
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| Week 3 After Fertilization |
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| How do cells know to move? |
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| Due to chemoattraction and chemorepulsion |
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Filters between epithelial and CT Controls cell growth, metabolism and differentiation |
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| 2 Derived components of Basement Membrane |
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Epithelial-basal lamina CT-lamina fibroretiularis Possible 3rd layer- lamina lucida |
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Protects, Absorbs, Secretes, Transports, Contracts, Filters, Sensory
Pretty abs seek turkey cubes for sandwiches. |
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Increase absorption 30 fold May be part or product of cell Enclosed in cytoplasm |
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Made of 10 doublets of microtubules w/ 1 in the center Arise from centriole and basal body Dynein and ATP used to cause motion Contained within membrane. |
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| Sugar coating used for recognition, adhesion, absorption, and protection |
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| General Epithelial attachments |
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Lateral-Cadherin based Basal-Integrin Based Zonula-Band Macula- A spot |
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&-Most apical -Tetraspanins make sealing strands- occludin claudins |
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| Adherens Junctions include |
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Zonula Adherens, Desmosomes, Hemidesmosomes 3 parts-transmembrane proteins, anchoring proteins, and cytoskeleton. |
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Needed for all other junctions to form Transmembrane cadherins bind to actin |
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Also called desmosomes Anchoring proteins attach to Intermediate filaments. |
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Channel called Conexon Made by 6 connexins. |
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Can happen in 4-5 days(gut) or 28 days(skin) Keratinocytes immediately fill in the gap. |
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| Epithelial Mesenchyme Transitions(EMTs) |
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Cells diminish E-cadherin expression, protrude out of epithelium and break down cell junctions. -Then the cell becomes mesenchymal and differentiates. An example is gastrulation |
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| How to tell the difference between secretory cells: |
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| It's all about the organelle content and expansion. |
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-Well developed rER. -Highly Polar: basal rEr and apical secretory granules |
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Well developed basal rEr and supranuclear Golgi Lots of mucin filled vesicles |
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-Hydrophillic -GAGs are repeating disaccharides(up to 40) -100s of GAGs per mucin -Becomes mucus when full of water -85% Carb |
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| Lipid(steroid) secreting Cells |
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-Well developed sEr -Free lipid vavuoles -Lots of mitochondria w/tubular cristae |
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| Ion and water transport secretion |
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-Folded membrane -Lots of mitochondria at folds -tight junctions between cells |
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Mucous Secretions
Serous Secretions |
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Mucous: viscous, slimy, glycosylated. ie goblet cells
Serous: watery, poorly or non glycosylated. ie sweat glands |
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-Hemotoxylin & Eosin(H&E)- Most common, nuclei/ribos/rER blue, cytoplasm/proteins pink -Diff-Quick-Stains blood cells -Orcein-Resourcein- elastic fibers black, nuclei gray -Silver Stain-Neurons black -Supravital-Stains reticulocytes, chromatin dark |
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| Two or more different tissues that have a certain function and shape |
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Aided by enzyme in trophoblast Also aided by uterine secretions |
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