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Blood Pressure Drugs
Cardiac Drug types
6
Medical
Undergraduate 2
06/07/2011

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Term
ACE Inhibitors
Definition
ACE Inhibitors

Captopril, enalapril, fosinopril, lisinopril, perindopril, quinapril, ramipril, trandolapril.

Block renin-angiotensin-aldosterone mechanism
Term
Angiotensin II receptor antagonists
Definition
Angiotensin II receptor antagonists

Candesarten, eprosarten, irbesarten, losarten.

"Antagonists of the angiotensin AT-1 receptor
* Decrease peripheral vascular resistance
* Inhibit aldosterone release"
Term
α1‐Adrenoceptor antagonists
Definition
α1‐Adrenoceptor antagonists

Prazosin, doxazosin, terazosin

"Block alpha receptors on arterioles and venules p
Inhibit sympathetic nervous system-mediated vasoconstriction and thereby reduces peripheral vascular resistance
Used in severe hypertensive crisis"
Term
Beta Blockers
Definition
Beta Blockers

Propranolol, oxprenolol, atenolol, metoprolol.

"Act by blocking β1 adrenergic receptors - Reduces cardiac output by decreasing heart rate and
myocardial contractility"
Term
Calcium channel antagonists
Definition
Calcium channel antagonists

Nifedipine, Amlodipine, Verapamil.

"Inhibit calcium ion channels and block entry of calcium
into vascular smooth muscle and myocardial cells
* Produces peripheral vasodilatation and also reduces
the force of myocardial contraction"
Term
Diuretics
Definition
Hydrochlorothiazide.

Diuretics

"Decreases blood pressure by
reducing blood volume
By acting on the kidneys to
increase urine flow"
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