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blood j
blood j
24
Anatomy
Undergraduate 1
11/13/2008

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Term
What is the first degree response that is formed by B cells undergoing mitosis?
Definition
Plasma cells-antibody factories
Term
What is second degree response when B cells undergo mitosis?
Definition
Memory cells-clones of B cells for next invasion
Term
What eliminates specific antigens?
Definition
Antibodies-secreted in blood by plasma cells
Term
What happens when antibodies are secreted in blood by plasma cells?
Definition
Eliminate specific antigens
Term
What binds to compliment binding site on antibody?
Definition
compliment
Term
What is MAC?
Definition
Membrane Attack Complex, C5 to C9
Term
What does a compliment cascade result in?
Definition
MAC membrane attack complex
Term
What is agglutination?
Definition
Clumping of blood
Term
What causes MAC-membrane attack complex?
Definition
Compliment cascade
Term
With regard to Ab2, what does it bind to?
Definition
B & C
Term
With regard to Ab3, what does it bind to?
Definition
C & A
Term
What results in blood typing?
Definition
Agglutination-clumping, mass not soluble
Term
When mass is not soluble-agglutination, what is the result?
Definition
Blood typing
Term
When there is no immune response possible, what is it called?
Definition
Neutralization
Term
What is the initial response?
Definition
Primary, 1st response to antigen
Term
What causes secondary response?
Definition
Memory cells
Term
How long do memory cells live?
Definition
20 years
Term
What is the structure of an antibody IgG?
Definition
4 polypeptide chains
2 heavy 50Kd identical
2 light 25 kd identical
Term
Whch polypeptde chain has 1 variable and 3 constant domains?
Definition
2 heavy chains
Term
Which polypeptide chain has one variable and one constant domain?
Definition
Light chain
Term
What does MAC do?
Definition
Forms a hole in foreign body or infected cell membrane
Term
What is leaking of intracellular components?
Definition
Lysis of cell
Term
What is clumping of blood?
Definition
Aggultination
Term
With Agglutination, what does Ab#1 bind to?
Definition
Ag A & B
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