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Blood Cells
Blood cells
19
Physiology
Graduate
09/19/2008

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Cards

Term
What is the difference between plasma and serum?
Definition
Plasma is the liquid of centrifuged blood. Serum is plasma minus the clotting factors.
Term
What are the four criteria for recognizing and distinguishing WBCs?
Definition
a) morphology of nuclei
b)presence/ absence of granules and their color
c) size of cell
d) relative abundance
Term
Name the granulocyte WBCs
Definition
Neutrophils, Eosinophils and Basophils
Term
Name the agranulocyte WBCs
Definition
Lymphocytes and Monocytes
Term
What is the most abundant WBC?
Definition
the Neutrophils (60-70% of all WBCs)
Term
Which is the largest WBC?
Definition
Monocytes are the largest
Term
Which WBC is responsible for phagocytosis?
Definition
Neutrophils. They are capable of creating reactive oxygen species (O2, H2O2 and HOCl) to help in that process
Term
Which WBC is chemotactic to parasites?
Definition
Eosinophils
Term
Define Hemopoiesis
Definition
Hemopoiesis is the formation of blood cells (from stem cells)
Term
What color bone marrow do adults have?
Definition
Adults have yellow bone marrow, which has low RBC production. Infants have red marrow, which makes lots of RBC. In times of need, adults may switch to red marrow.
Term
There are six stages in the erythropoietic series (proerythroblast -> erythrocyte). What is the best way to distinguis between the different phases?
Definition
Size. Erythrocytes are the smallest. Only reticulocytes and erythrocytes are anucleated.
Term
Platelets (aka __________) are disk shaped cell fragments of much larger ____________.
Definition
1) thrombocytes
2) megakaryocytes
Term
List four major features of RBCs
Definition
1) no nucleus
2)durable
3) deformable (can compress)
4)elastic (can return to original shape)
Term
What is an anemia?
Definition
Anemia is a decreased functional capacity of blood to deliver O2 to tissues/cells
Term
Anemia may be caused by a decrease in numbers of RBCs. What can cause a decrease in RBCs?
Definition
RBC decrease can be caused by:
a) blood loss
b)hemolytic anemia (abnormal breakdown of RBCs)
c) ineffective erythropoieses (new RBC formation)
Term
Anemia may be caused by an insufficient amount of functional hemoglobin. What causes dysfunctional Hb?
Definition
a) hemoglobinopathies
b) defect in heme synthesis
c) iron deficiencies
Term
_______________ is an anemia associated with erythrocytes of reduced size and hemoglobin content.
Definition
Microcytic hypochromic anemia
Term
__________ is an anemia caused by low numbers of large RBCs.
Definition
Macrocytic anemia
Term
In a CBC, the ______________ gives the volume of red blood cells/volume of blood.
Definition
Hematocrit
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