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Asthma Theophylline
Asthma Theophylline
5
Pharmacology
Professional
09/16/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
How does thelophylline work?
Definition

Blocks phosphodiesterase causing increase in cyclic AMP (cAMP) which promotes release of epinephrine from adrenal cells. This results in bronchodilation, diuresis, CNS and cardiact stimulation

Term

Theophylline is a good drug for asthma but it has many side effects. What are some signs of toxicity?

Definition

Persistent and repetitive vomiting, ventricular tachycardias, seizures

Term
IV aminophyline contains what % of theophyline?
Definition
80%
Term
What is unique about theophylline pharmacokinetics?
Definition

Has first order kinetics, followed by Michaelis - Menton (or saturable) kinetics (similar to phenytoin and voriconazole). A smalla increase in dose can result in a large increase in the theophylline concentration

 

Term
What drugs can increase or decrease theophylline?
Definition
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