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Anxiety Background & Treatment
Anxiety Background & Treatment
40
Pharmacology
Professional
08/26/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Namecommon types of anxiety disorders.
Definition

generalized anxiety disorder (GAD)

Panic disorder (PD)

Social Anxiety Disorder (SAD)

Obsessive Compulsive disorder (OCD)

Post Traumatic Stress Disorder (PTSD)

 

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Term
Bupropion has anxiety indication for?
Definition
SAD
Term
Citalopram has anxiety indication for?
Definition
OCD, PD
Term
Escitalopram has anxiety indication for?
Definition
GAD
Term
Fluoxetine has anxiety indication for?
Definition
OCD, PD
Term
Fluvoxamine has anxiety indication for?
Definition
OCD, SAD
Term
Paroxetine has anxiety indication for?
Definition
GAD, OCD, SAD, PD, PTSD
Term
Sertraline has anxiety indication for?
Definition
OCD (peds and adults), PD, SAD
Term
Duloxetine has anxiety indication for?
Definition
GAD
Term
Venlafaxine has anxiety indication for?
Definition
GAD, PD, SAD
Term
Doxepin has anxiety indication for?
Definition
Anxiety
Term
Imipramine has anxiety indication for?
Definition
PD
Term

Anxiety disorders are primarily treated with SSRIs, SNRIs or tricyclic antidepressants.

Definition
Statement. Not a question.
Term
Fluvoxamine was the first SSRI indicated for OCD but it is rarely used due to?
Definition

Drug interaction potential. Prescribers tend to use the newer agents that have less drug interactions and smaller dosing ranges.

Term
How is hydroxyzine used as it relates it relates to anxiety?
Definition

Hydroxyzine (Vistaril) is occasionally used for short - term anxiety. This is a sedating antihistamine, and works by sedating the patient, rather than treating any underlying cause. It should not be used long term.

Term
Pregabalin and anxiety
Definition

Pregabalin (Lyrica) is sometimes used for anxiety, and can be especially useful if a patient has neuropathic pain. It is scheduled C-V since it is slightly euphoric - which can have a calming effect.

Term
Propranolol and anxiety
Definition

Propranolol (Inderal) is used to reduce symptoms of stage fright, or performance anxiety (tremor, tachycardia). Use caution since CNS effects (confusion, dizziness) may be present.

Term
Buspirone and anxiety
Definition

Buspirone (Buspar) is an option for anxiety for patients who do not respond to antidepressants or in a patient at risk of abuse with benzodiazepines, or in addition to other therapy. It is a commonly used agent.

Term

Benzodiazepine (BZD) are often used for anxiety symptoms. They provide fast relief for acute symptoms.

Definition
Statment. Not a question.
Term
In what situations are BZDs appropriate?
Definition

short - term situations in which axiety is acute and can cause extreme stress, prevent proper sleep, and disrupt life. This is could be the recent death of a loved one, an earthquake, a moter vehicle accident, or other stressfull situations. In such cases they re used less than 1 - 2 weeks and can be discontinued.

Term
Do BZDs treat anxiety?
Definition

BZDs cover up, but do not treat, the causes of anxiety, and, in most cases, should not be used long - term.

Term
Brand name for lorazepam
Definition
Ativan
Term
Brand name for Alprazolam
Definition
Xanax
Term
Brand name for Clonazepam
Definition
Klonopin
Term
Brand name for Diazepam
Definition
Valium
Term
What schedule is lorazepam?
Definition

CIV potential for abuse

 

Term
Does dependence occur with use of BZDs?
Definition

Physiological dependence and tolerance develoop with chronic use

Term
What occurs when discontinuing BZDs?
Definition
Withdrawal symptoms when discontinued.
Term
Which BZDs are best for the elderly?
Definition

L-O-T (lorazepam, oxazepam, and temazepam): these are considered less potentially harmful for elderly or with liver impairment since they are metabolized to inactive compounds (glucunoids).

Term
Which BZDs are used for alcohol withdrawal?
Definition

Chlordiazepoxide (Librium) and Diazepam (Valium)

 

Term
[image]
Definition
Statement. Not a question.
Term
Main drug interaction concern with BZDs?
Definition

Additive effects with sedating drugs, including most pain medicines, muscle relaxants, antihistamine, the antidepressant mirtazapine (Remeron), trazodone, alcohol, among others

Term
When are BZDs normally taken?
Definition

Only if used for insomnia: This medication should be taken before bedtime (for anxiety is taken prn)

Term
Long term use of BZDs can lead to tolerance, meaning?
Definition
medication may not work as well and may require different dosing.
Term
What is Busprione?
Definition

5-HT1 partial agonist: Not Controlled, NO Abuse or Physiological Potential - this, rather than a higher efficacy over BZDs, makes buspirone a widely used agent.

 

Term

[image]

 

Definition
Statement. Not a question.
Term
Do not use Buspirone with MAO - I inhibitors.
Definition
Statement. Not a question.
Term
When to decrease dose of buspirone?
Definition

decrease dose with erythromycin, diltiazem, verapamil; consider dose reduction with any 3A4 inhibitor.

Term
What may cause an increase in the buspirone dose?
Definition

3A4 inducers, including rifampin, may require an increase in the buspirone dose.

Term
Can the busiprone tablets be divided?
Definition

Buspirone comes in a Dividose tablet designed to make dose adjustments easy. Each table is scored and can be broken accurately on the score lines into thirds. It snaps into pieces with finger pressure.

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