Shared Flashcard Set

Details

Antivirals
antiviral agents (non-hiv)
17
Nursing
Undergraduate 3
12/13/2011

Additional Nursing Flashcards

 


 

Cards

Term
Herpes
Definition
HSV (herpes simplex virus) and varicella-zoster are members of the herpes virus group
vaccinations
HSV: genitalia, mouth and face
VZV:painful, chicken pox or shingles.
Term
Acyclovir
Definition
1st line for most herpes
active only for herpes
suppress DNA synthesis
no serious side effects, topical oral or IV
Term
Hepatitis
Definition
most common liver disorder
ABCDE and G
all cause acute hepatitis but only bc&d cause chronic (monitor LFT & viral load)
Hep C is leading cause of transplant
Term
Hep C
Definition
from blood transmitting
slow progression, liver failure, cancer and death
most effective treatment is pegylated interferon alfa combo with riboflavin
no hep c vaccine
6 genotypes but mostly type 1 (least responsive to treatment)
Term
interferon Alfa prep
Definition
Sub Q
multi effects on viral replication cycle:
binding to receptors on the host cell, blocks viral entry into the cells, synthesis of viral messenger rna and viral proteins and viral assembly and release.
Term
interferons
Definition
conventional - short half-life, must be administered frequently, 3xweek

long acting- long half life, weekly admin, pegylations: conjugating a conventional interferon with a polyethylene glycol (which serves to delay elimination)
Term
adverse effects of interferon alfa
Definition
flu-like
neuropsychiatric (depression, SI)
thyroid dysfunction
heart damage
bone marrow suppression
Term
effects of hep c treatment
Definition
produces a normalization of serum ALT
reduces serum hcv rna
adverse: hemolytic anemia and preg cat x
Term
Flu
Definition
Influenza a- 96% of cases
b- 4%
spread via droplets
vaccine protection takes 1-2 weeks
~6 mos protection
Adverse: transient effects, flu like, guilain-barre, bell's palsy
Term
H1N1
Definition
hast wo genese from pig flu, one from avian, one from human = quadruple reassortant virus
Term
Acute Respiratory Infection (ARI)
& Influenza like illness (ILI)
Definition
ARI: two or more- fever,cough, sore throat and rhinorrhea

ILI: fever and cough or sore throat
Term
Tamiflu/ relenza
Definition
pts who initially present with severe illness or who's condition deteriorates begin immediately w/o labs

pts at risk for serious disease including underlying medical conditions asap after onset without labs
Term
Chlamydia
Definition
most common bac STD
adults: azithromycin 1x, doxycycline 100mg BIDx7
preg: erythromycin 500mg QIDx7 or azithromycin TIDx7
infants risk for conjunctivitis and pneumonia: e-mycin 12.5/kg QIDx14 and topical drops
preadolescent childrens suspect abuse
Term
gonorrhea
Definition
treatment with cipro, levanox, or ceftriaxone
Term
Pelvic Inflammatory Disease
Definition
infertility
abdominal pain, vaginal discharge and fever
caused by gonorrhea or trachomatis or both
broad spec needed
hospitalized need cefoxitin 2g IV Q6h and Doxy 100mg IV Q12h x 14days
Term
syphilis
Definition
spirochete treponema pallidum
Primary: enters by mouth vag or urethra. Primary lesion called a chancre sore
2nd: 2-6 wks: skin lesions and ili, enlarged lymoh nodes and joint pain
3rd: 5-40 years: changes to any organs
treat with Pen G 2.4 million units IM once
Term
BV
Definition
most commonly gardnerella vaginalis
fishy odor and secreations and pH > 4.5
oral or intravaginal metronidazole or clindamycin
Supporting users have an ad free experience!