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Antimicrobial TARGETS/drugs used
Drugs and where they effect cell wall/cell membrane function
10
Microbiology
Undergraduate 1
03/27/2012

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Cards

Term
Targets of antimicrobial agents overall effect
Definition
*cell membrane
*cell wall
*protein syntheis
*metabolic reactions
Term
cell wall
Definition
*penicillin *cephalosporin *vancomycin *bacitracin *monobactams *fosfomycin *cycloserine
Term
inhibit replication & translocation
Definition
*quinolone (Cipro) (inhibit unwinding)
Term
inhibit RNA polymerase
Definition
*rifampin
Term
inhibit folic acid metabolism
Definition
*sulfa drugs & trimethoprime
Term
cell membrane
(EUK - sterols, fungi)
Definition
*polymyxins & Amphotericin B & nystatin
Term
cell wall (gram neg)
Definition
polymyxins
Term
targeted Ribosomes/block protein synthesis: the 30S subunit
Definition
*aminoglycosides *tetracycline *streptomycin *Amikacin
Term
targeted Ribosomes/block protein synthesis: 50S subunit
Definition
*Chloramphenicol *erythromycin *clindamycin *Oxalolidinones
Term
Target bacterial cell wall/Pepticoglycan
Definition
*penicillin (the cross linking)
*cephalosporin
(cause cell walls to lyse)
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