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Anatomy and Physiology of Bone
n/a
136
Biology
9th Grade
05/05/2011

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Term
Define: osteon
Definition
functional unit of bone
Term
where do osteocytes lie?
Definition
lacunae
Term
Lacunae are interconnected by _________
Definition
canaliculi
Term
the central canal (of the osteon) contains......
Definition
blood vessels, lymphatic vessels, and nerves
Term
What in your bones produces blood cells?
Definition
RED bone marrow
Term
In infants, red marrow is...
Definition
present in cavities off all bones
Term
In adults, red marrow is present in....
Definition
spongy bone of skull, sternum, ribs, vertebrae, and ends of long bones
Term
Describe: matrix
Definition
gel-like with lacunae for chondrocytes
Term
Three types of cartilage?
Describe
Definition
hyaline: firm, white, a. found in ends of long bones, nose, and ends of ribs
fibrocartilage: stronger, thick collagen bands, and can withstand both pressure and tension.Found in intervertebral disks
Elastic- most flexible, contains elastin fibers. Found in external ears and epiglottis
Term
Define: dense fibrous connective tissue
Definition
very strong rows of fibroblasts separated by collagen fibers that compose structures that connect bone to bone and muscles and bones
Term
Name a similarity/difference between ligaments/tendons
Definition
DIFFERENCE: tendons connect MUSCLE to bone while ligaments connect BONE to bone
Similarity is that they're both dense fibrous connective tissue
Term
[image]
Definition
[image]
Term
bones are classified by _____
Definition
shape
Term
Define: periosteum
Definition
fibrous connective tissue
Term
define: epiphysis
Definition
-widened end of a long bone
-composed spongy bone
-contains red marrow
Term
define: diaphysis
Definition
-shaft of long bone
-composed of compact bone
-encloses medullary cavity
Term
How often does bone remodeling occur?
Definition
every 8-10 years
Term
Define: osteoClasts
Definition
break down bone
(to put in calcium, because you need to maintain certain levels of calcium in blood to contract your muscles)
Term
define: osteoBlasts
Definition
pick up calcium from blood and deposit it in new bone
Term
Remodeling can change bone ______
Definition
thickness
Term
What causes wear and tear to bones/to remodel bone?
Definition
hormones, physical use
Term
Define: osteoporosis
Definition
weak, thin bones which fracture easily
Term
Define: ephiphyseal plate
Definition
growth plate that allows bone to grow longer using cartilage
Term
Why do people shrink?
Definition
Vertebral disks lose mass
Term
Functions of bones and which bones do what?
Definition
structural support:
bones of lower limbs, especially femur
protection of soft body parts:
skull, rib cage
production of blood cells:
red marrow in ends of long bones, sternum, pelvis
storage of minerals and fat:
calcium phosphate in bone matrix, fat in yellow marrow
locomotion:
along with muscles
Term
Two types of skeletal bones?
Where found?
Definition
axial- skull, vertebral column, rib cage
appendicular- bones of limbs and the limb girdles (shoulders and hips)
Term
Shapes of bones? (where?)
Definition
LONG- bones of limbs
SHORT- cube shaped bones of digits
ROUND- Patella
IRREGULAR- vertebrae
Term
Relating to shape, all bones have WHAT?
Definition
depressions and protuberances (processes) for attachment of muscles
Term
What is the "big hole" in your head and what does it do?
Definition
your foramen magnum. your spinal cord comes out of it
Term
Define: incomplete ossification in infants
Definition
fontanels
Term
Define: cranial bones of the skull
Definition
bones that protect the brain
Term
How may vertebrae do you have?
Definition
33
Term
How many curvatures do you have in your spine?
Definition
4
Term
where do spinal nerves exit?
Definition
through the intervertebral foramina
Term
the spinal cord passes through the _____
Definition
vertebral canal
Term
types and #s of vertebrae?
Definition
7 cervical
12 thoracic
5 lumbar
----
5 sacral
3-5 coccyx
Term
define: intervertebral disks
Definition
-composed of fibrocartilage
-absorb shock, allow flexibility
-can herniate and rupture
Term
when intervertebral disks herniate/rupture, what does that do?
Definition
puts pressure on spinal cord
Term
Define: rib
Definition
each originates at a thoracic vertebra and proceeds to anterior thoracic wall
Term
Types of ribs, #s of each
Definition
true- 7, upper pair articulate directly w/ sternum via cartilage
false- 3 -first join a common cartilage and then to the sternum
floating- 2 - last pair that do not articulate w/sternum @ all
Term
where is the sternum?
Definition
midline
Term
Parts of sternum, describe
Definition
MANUBRIUM - articulates w/ clavicle and first pair of ribs
BODY- point of junction between manumbrium and body is an important landmark because it IDs second pair of ribs, which allows the counting of ribs to determine the apex of the heart
XIPHOID- has a process for muscle attachment
Term
Different articulations, describe, where
Definition
Fibrous- immovable
-sutures between bones of skull
Synovial- freely movable
-stabilized by tendons
-membranes line joint capsule
-contain bursa
-contain menisci
Term
DEFINE BURSA
Definition
fluid-filled sacs that decrease friction between tendons and ligaments
Term
Define: menisci
Definition
cartilage between bones w/in the joint; shock absorbers (ex: knee)
Term
Types of synovial joints?
How they move?
Exs?
Definition
Hinge joints: 1 direction (knee)
Ball and socket: permit movement in all planes (hip)
pivot: rotational (joint between radius and ulna)
Term
Define: osteoarthritis
Definition
-deterioration of an over-worked joint
-wearing away of articular cartilage
-joint replacement
-glucosamine and chondroiton sulfate
Term
Types of movements at synovial joints?? DEMONSTRATE
Definition
flexion (forearm toward arm), extension (forearm away from arm), abduction (arms sideways, away from body), adduction (arms back to the body), rotation, (head to answer "no), pronation (foot rolls inside), supination (foot rolls outside)
Term
Define: antagonist muscle
Definition
a muscle that opposes the action of another; "the biceps brachii and triceps brachii are antagonistic muscles"
Term
Define: fascia
Definition
connective tissue that covers skeletal muscles
Term
describe skeletal muscles
Definition
-stiated
-voluntary
-attached to bone by tendons
-covered by fascia
-muscles are arranged in functional groupings
-most muscles have an antagonist
Term
What's different about your muscles lifting your shoe versus your muscles picking up a small child?
Definition
You'd use more muscles for the small child. Hey. What are you doing with that child anyway?????
Term
Each muscle cell is called a _____
Definition
muscle fiber
Term
Define: sarcoplasmic reticulum
Definition
endoplasmic reticulum running throughout muscle fiber that STORES CALCIUM IONS
Term
Define: T tubules
Definition
-extend into cell from the sarcolemma
-carry electrical impulse into muscle, allowing it to contract in unison
Term
Define: myofibrils
Definition
-composed of contractile filaments
-arranged in bundles surrounded by endoplasmic reticulum
-contains actin and mysoin
Term
define: sarcomere
Definition
-functional unit
-contractile unit of muscle
Term
Describe myofibrils and sarcomeres
Definition
-myofibrils are cylindrical
-striated appearance due to arrangement of contractile filaments
-
Term
What is a unit of contraction?
Definition
sarcomere
Term
_________is a thick filament
_________is a thin filament
Definition
actin
myosin
Term
How does each myosin molecule look?
Definition
like a golf club
straight portion ending in a double globular head or crossbridge
Term
describe actin
Definition
-consists of 2 intertwining actin filaments
-tropomyosin and toponin are associated proteins
Term
Define: neuromuscular junction
Definition
where nerve meets muscle
Term
What does AP stand for?
Definition
Action Potential
(Electric stimulus)
Term
Define: synaptic cleft
Definition
space for when nerve meets muscle
Term
Describe the role that sliding filaments have in muscle contraction
Definition
-Upon stimulation, action potential (AP) spreads along membrane
-AP travels down T tubules into muscle fiber
-calcium is released from sarcoplasmic reticulum
-sarcomeres w/in myofibrils shorten, causing a contraction of muscle fiber
-actin filaments slide past the myosin filaments and approach one another
-ATP supplies the energy
-myosin filaments break down ATP and have crossbridges that pill the actin filaments toward the center of the sarcomere
Term
[image]
Definition
[image]
Term
When do muscles relax?
Definition
when impulse stops coming from nerves
Term
what do neurotransmitters do?
Definition
open up the gate so that sodium ions rush in, and calcium is released from storage
Term
Define: rigor mortis and why it happens
Definition
-muscles contracted after death
("the stiffness of death")
-when we die. production of ATP stops. No more ATP, no more removal of myosin, locking muscle
Term
[image]
Definition
[image]
Term
[image]
Definition
[image]
Term
What is the role of actin and myosin in muscle contraction?
Definition
tropomyosin winds through actin blocking binding sitees
-troponin is located at intervals along actin
-when calcium ions are released, they bind to troponin
-causes troponin to shift position and unblock binding sites
-exposes binding sites fror myosin crossbridges
-globular heads have ATP binding sites
-ATPase splits ATP to ADP and P
-Heads now bind to sites on actin
-relaxation occurs when impulses stop and calcium is taken up by sarcoplasmic reticulum
Term
How does the body get energy for muscle contraction? (fastest)
Definition
Creatine phosphate breakdown (substrate level phosphorylation):
-high energy compoud builts up at rests
-can provide energy for about 8 seconds of intense activity
-regenerates ATP - when creatine phosphate breaks down to creatine, energy is released to phosphorylate ADP to ATP
Term
Where does muscle contraction get most energy from?
How does this work?
Definition
cellular respiration
-muscle cell can use glucose from glycogen and fatty acids from fat in cell respiration pathway
-occurs mitochondria and requires oxygen
-muscle cell has myoglobin-has higher affinity for oxygen than hemoglobin
-allows temporary storage of oxygen
Term
What is last resort for energy for muscle contraction?
Definition
fermentation
-glucose is broken down in glycolysis to pyruvate, which is converted to lactic acid
-2 ATP / glucose
-when lactic acid build up, makes cytoplasm more acidic
-if fermentation occurs for more than 2-3 minutes cramping occurs
Term
What are the types of tissues in your body?
Definition
-muscular
-cardiovascular
-epithelial
-connective
Term
Cancer of the ____ tissue is...
a. epithelial
b. blood
c. lymphoid
Definition
a. carcinoma
b. leukemia
c. lymphomas
Term
Functions of epithelial tissue?
Definition
-protection - protects from pathogens
-secretion - mucus from digestive tract
-absorption - small intestine absorbs food
-filtration - tissue of kidneys forms urine
-excretion - " "
Term
Define: squamous
Definition
ooooooo
-flat
Term
Where is squamous? cuboidal? columnar? tissue found?
Definition
squamous - lungs, lining of blood vessels
cuboidal - kidneys
columnar - lines digestive tract
Term
Epithelial tissue can be one layer _________ or many _____________
Definition
Epithelial tissue can be one layer (simple) or many (stratified)
Term
What is _____ really good at? Where?
a. simple cuboidal
b. simple squamous
c. stratified squamous
Definition
a. excretion (kidneys)
b. diffusion (lung tissue)
c. protection (skin)
Term
Define: pseudostratified ciliated columnar epithelial tissue
Definition
-1 layer of cells (it looks like 2)
-each cell touches the basement membrane
-found in trachea
-secretes mucus that traps dirt
Term
Which organ is both endocrine/exocrine?
Why?
Definition
PANCREAS
-endocrine - insulin into bloodstream
-exocrine - digestive enzymes into duct to small intestine
Term
Three types of junctions between cells? (describe)
Definition
-tight - impermeable
-gap - allow molecules to pass through
-adhesion - (desmosome): ilaments pass through adjacent membranes
Term
Define: matrix
Definition
-material found between connective cells
-contains collagen, hyaline, reticular, and elastic fibers
Term
Types of connective tissue?
Definition
-adipose tissue
-cartilage
-bone
Term
What are adipose tissues filled with?
Definition
oil
Term
Where do cartilage cells live?
Definition
lacunae
Term
What is a cartilage cell called?
Definition
chondrocyte
Term
draw compact bone
Definition
[image]
Term
The hard matrix of bone is made of what?
Definition
-inorganic salts (like calcium)
-oxygen
Term
Types of bone? Describe
Definition
-compact bone - dense bone made of osteons
-spongy bone - bony bars w/ spaces
Term
Where is hyaline cartilage found?
Definition
-over the ends of bones at movable joints
-ends of ribs
-supportive material in larynx
-trachea
-bronchi
-fetal skeleton
Term
Where is elastic cartilage found?
Definition
-external ear and epiglottis
Term
Where is fibrocartilage found?
Definition
-pubic synthesis
-meniscus
-invertebral disks
Term
What does blood do?
Definition
-transports oxygen, nutrients, and waste
Term
What is the percentage of plasma in the blood?
Definition
55%
Term
What does plasma consist of?
Definition
-water
-proteins
-ions
-salts
-vitamins
Term
What is the shape of RBCs?
Definition
-biconcave disk
Term
What are the fibers prevalent in muscular tissue?
Definition
-actin
-myosin
Term
Define: skeletal muscle
Definition
-voluntary
-fibers have many nuclei
-striated
Term
Define: smooth
Definition
-involuntary
-no striations
-found in intestine, stomach, and esophagus
-involved in swallowing, GI tract functions
-short fusiform cells
-one central nucleus
-nonstriated
Term
Define: cardiac muscle
Definition
-involuntary
-striations
-1 nuclei/cell
-connected to each other at intercalated disks
Term
Functions of nervous tissue?
Definition
-sensory input
-integration of data
-sensory output
Term
Name and describe 3 types of neurologia cells
Definition
-microglia -eat bacteria, cell debris
-astrocytes - provide nutrients to neurons
-oligodendrocytes - form myelin (insulation)
Term
Name to major body cavities
Definition
-thoracic
-dorsal
Term
What cavities are located w/in the ventral cavity?
Definition
Includes:
-thoracic cavity
-Abdominal "
Term
Define: thoracic cavity:
Definition
chest cavity containing heart and lungs
Term
Define: abdominal:
Definition
contains digestive, excretory, and reproductive organs
Term
The thoracic and abdominal cavity are separated by the....
Definition
diaphragm
Term
What cavities are located w/in the dorsal cavity?
Definition
-cranial cavity
-vertebral canal
Term
Define: cranial cavity
Definition
-houses brain
Term
Define: vertebral canal
Definition
houses spinal cord
Term
Define: body membrane
Definition
thin layer of epithelium overlying a loose connective tissue
Term
four types of membranes?
Definition
-mucous
-serous
-synovial
-meninges
Term
Define: mucous membranes
Definition
-line the digestive, respiratory, urinary, and reproductive systems
-contain goblet cells that release mucus
Term
Define: serous membrane
Definition
-line the thoracic and abdominal cavities
-Contains pleura
-" peritoneum
Term
Define: pleura
Definition
-lines thoracic cavity, covers lungs
Term
Define: periotoneum
Definition
-covers abdominal cavity and organs
Term
Define: synovial membranes
Definition
-lines free movable joint cavities
-produces synovial fluid to lubricate joint
Term
Define: meninges
Definition
membrane covering brain and spinal cord
Term
What is the system of hair/skin/nails?
Definition
integumentary
Term
What is the system for hormonal glands called?
Definition
endocrine
Term
Functions of the integumentary system?
Definition
-protection from pathogens, water loss, and UV light
-regulate body temp (sweating)
-makes vitamin D
Term
What makes melanin?
Definition
melanocytes
Term
Describe the epidermis (5)
Definition
-contains keratin, which waterproofs skin
-contains melanocytes
-contains 5 layers
-no blood vessels
-gets nutrients by diffusion
Term
Name the layers of the epidermis layer
Definition
-top stratum corneum (dead)
-stratum lucidum (dead)
- " granulosum (dead+living)
- " spinosum (living)
-bottom stratum basale (living)
Term
Describe dermis
Definition
-contains collagen
-elastic fibers
-contains blood vessels
-contains nerve endings
Term
What is the subcutaneous layer composed of?
What does it do?
Definition
-composed of loose conntective tissue and fat
-fat provides thermal insulation and physical protection
Term
Nail cells are filled with ....
Definition
keratin
Term
What makes hair "stand on end"
Definition
arrector pili muscle
Term
Define: sebaceous gland
Definition
-associated with each hair follicle
-secretes sebum to moisturize skin
Term
What is another name for the sweat gland?
Definition
sudoriferous gland
Term
What is positive/negative feedback, exs?
Definition
negative- change in body, body does something to maintain homeostasis
ex: body temp
Positive: brings abt greater change in the same direction
ex: during pregnancy, baby pushes on cervix to initiate labor. Message is sent to the brain that causes the release of oxytocin that causes even more contractions
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