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Abnormal RBC's (Descriptions)
Hematology
18
Biology
Undergraduate 4
11/06/2011

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Term
Echinocytes (Description)
Definition
RBC’s with evenly-spaced projections
Results from an increase in the outer lipid bilayer of the RBC membrane
Some can be revert back to normal
Term
Stomatocytes (Description)
Definition
Uniconcave Discs
Results from an increase in the inner lipid bilayer of the RBC membrane
Term
Spherocytes (Description)
Definition
No biconcavity, no central pallor, increased osmotic fragility
Circular RBC’s
Results from macrocytes biting out inclusions (Pitting)
Normocytic
Term
Shistocytes (Description)
Definition
The result of repeated putting or fibrin cutting
Found in people who have intravascular hemolytic anemia
-The blood cell gets cut in half by fibrin in the blood vessels
Term
Acanthocytes (Description)
Definition
Have un-even, thorn-like projections
Not evenly spaced around the cell
Caused by altered lipids in the RBC
Normal life span
Term
Leptocytes (Description)
Definition
Hypochromic
Term
Codocytes (Description)
Definition
Look like bulls-eyes
Can be artifacts
Have decreased osmotic fragility
Term
Dacrycytes (Description)
Definition
Elongated at one end
Can be artifacts
Term
Drepanocytes (Description)
Definition
Elongated crescent-shaped with pointed ends
Decreased osmotic fragility and decreased mechanical fragility
Term
Elliptocytes (Description)
Definition
Elongated cells
Term
Keratocytes (Description)
Definition
Concavity on one side and 2 hornlike projections on either end
Formed by pitting or by impalement on fibrin strands
Term
Knizocytes (Description)
Definition
2 concavities
Formed by pitting or by impalement on fibrin strands
Term
Basophilic Stippling (Description)
Definition
Bluish-black granular inclusions
Term
Howell-Jolly Bodies (Description)
Definition
Dark purple or violet spherical granules
DNA fragments
Usually only 1 per cell
Look like a dot on the cell
Term
Cabot Rings (Description)
Definition
A ring on the cell
Term
Heinz Bodies (Description)
Definition
Purple bodies
Not seen with Wright’s Stain
Have to use New Methylene Blue
Made up of denatured hemoglobin
Term
Sideroblasts and Siderocytes (Description)
Definition
RBC’s with iron granules
Stained with Prussian Blue or Iron Stain
Look for them in the bone marrow to see if iron stores are normal
Term
Pappenheimer Bodies (Description)
Definition
Iron-containing granules at the periphery of the cell
Visible with Wright and Prussian Blue Stain
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