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AA and Kin
Muscle Proteins
12
Biology
Undergraduate 3
02/06/2011

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Term
Myosin heavy chain
Definition
Molecular motor for muscle contraction—binds with actin to generate contraction force.
Term
Actin
Definition
Binds with myosin to translate force and shorten the sarcomere
Term
Tropomyosin
Definition
Regulates the interaction between actin and myosin; stabilizes actin filament
Term
Troponin
Definition
Influences the position of tropomyosin; binds with calcium ions
Term
Myosin light chain
Definition
Influences the contraction velocity of the sarcomere; modulates the kinetics of crossbridge cycling
Term
Nebulin
Definition
Anchors actin to Z discs
Term
Titin
Definition
Creates passive tension within the stretched sarcomere; acts as molecular “springs”
Term
Desmin
Definition
Helps to stabilize the longitudinal and lateral alignment of adjacent sarcomeres
Term
Vimentin
Definition
Helps maintain periodicity of Z discs
Term
Skelemin
Definition
Helps stabilize the position of M lines
Term
Dystrophin
Definition
Provides structural stability to the cytoskeleton and sarcolemma of the muscle fiber
Term
Integrins
Definition
Stabilizes the cytoskeleton of the muscle fiber
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