Details Title: A&D 2010: Mycobacteria Description: Mycobacteria Total Flash Cards: 18 Created: 01/27/2007 08:05:11		New Users: To study from this flashcard set, or to create your own your own study flash cards, REGISTER HERE. Existing Users: CLICK HERE. Additional Medical Flashcards
Cards in this set: Term Treatment for tuberculosis Definition * Isoniazid * Rifampin * Ethambutol Mnemonic: Get irate about tuberculosis; treat it with IRE. Term Rifampin mechanism of action and side effects Definition * Inhibit DNA-dependent RNA polymerase (RNA pol II) * Induce CYP Term Isoniazid mechanism of action and side effects Definition * Inhibit mycolic acid synthesis * Hepatic and peripheral nerve toxicity Term Ethambutol mechanism of action and side effects Definition * Inhibit mycolic acid synthesis * Ocular toxicity (red-green issues) Term Common etiological agent of chronic unilateral adenitis in children Definition Mycobacterium avium complex Term Effect of Mycobacterium avium complex on patients with AIDS Definition Bloodstream infections Term Treatment of Mycobacterium avium complex Definition * Azithromycin * Rifampin-like drugs Term Organs affected by M. leprae Definition Cold surfaces: * Peripheral nerves * Skin * Mucous membranes Term Which mycobacterial disease is known to affect armadillos? Definition Leprosy (M. leprae) Term Type of immune response to lepromatous leprosy Definition Humoral (little cell-mediated response) Term Characteristics of lepromatous leprosy Definition * Diffuse or nodular lesions * Sensory loss (due to nerve damage) * Mostly humoral immune response * Many acid-fast bacilli (AFBs) Term Characteristics of tuberculoid leprosy Definition * Few, well defined lesions * Few acid-fast bacilli (AFBs) * Mostly cell-mediated immune response * Spontaneous regression common in children (90%) Term Treatment of leprosy Definition * Rifampin-like drugs (RNA pol II inhibitors) * Dapsone (folate synthesis inhibitor) Term Characteristics of mycobacteria Definition * Acid-fast * Strict aerobe * No capsule * Intracellular survival * Slow growth Term Characteristics of Actinomycetes Definition * Gram-positive, weakly acid-fast * Anaerobic * Long, branching filaments * A. israelii is normal mouth flora Term Disease characterized by cervicofacial disease, firm nodules, and pus containing sulfur granules. What's it called and how is it treated? Definition Actinomycosis; treated with long course of penicillin Term Characteristics of Nocardia Definition * Gram-positive; weakly acid-fast * Aerobic Term Opportunistic bacterial infection that presents with skin nodules, pneumonia, and brain abscesses. What's it called and how is it treated? Definition Nocardia; treat with long course of sulfonamides