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48. Body Fluid Compartments and Exchange
Brennan
5
Biology
Graduate
10/08/2011

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Term
Total Body Water (TBW)
Definition
Consists of ICF (2/3) and ECF (1/3). Makes up for 60% of weight in males, 50% in females.
Term
ECF
Definition
Consists of
1. Interstitial Fluid (75%)
2. Plasma (20%)
3. Transcellular fluid (5%)
Small solutes in interstitial fluid and plasma can freely equilibriate.
Term
Volume Balance
Definition
Refers to ECF, plasma, or effective circulating volume.
Determines whether organs are receiving enough perfusion.
ECF should be closely matched to effective circulating volume, is not in disease states.
Na consumption is the main determinant of volume balance.
Term
Change in water balance
Definition
Results in change of osmolarity of ECF and ICF, ECF volume is barely affected.
Term
Change in Na balance
Definition
Results in change in ECF volume, osmolarity stays the same.
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